导师简介

姓名:王东文性别:男政治面貌:中共党员
学历:研究生学位:博士职称:教授/主任医师
博、硕导师:博士生导师和硕士生导师本岗位工作年数:30
研究方向:泌尿系肿瘤的临床诊疗与基础研究
荣誉称号:国务院特贴专家、百千万人才、有突出贡献中青年专家、白求恩式好医生、MDT卓越导师、国家级领军人才
学术任职:中华医学会泌尿外科分会(CUA)全国常委兼激光学组副组长、亚洲男科学会副主席、中国医学装备协会泌尿外科分(CUEA)副主委、中国研究型医院学会泌尿外科学专业委员会常委
近五年承担科研课题情况:
例如:中央引导地方科技发展资金项目(自由探索类基础研究) 项目名称:脊髓损伤后膀胱功能障碍的代谢组学研究,项目编号: YDZJSX2022A065
1、国家自然科学基金项目名称:纤维细胞外泌体中内质网应激相关凋亡miRNA介导糖尿病膀胱进展的分子机制研究项目编号:81970662
2、国家癌症中心重点项目 项目名称:ICG共轭偶联PSMA在机器人/腹腔镜前列腺癌手术治疗中实时精准定位及特异性研究项目编号:SZ2020ZD003
3、中国博士后科学基金 项目名称:前列腺癌早期筛查与诊断的血清循环miRNA筛选及其分子功能研究
4、深圳市恶性肿瘤临床医学研究中心项目 项目名称:深圳市保膀胱联盟构建和膀胱癌外泌体监测临床研究
代表性论著及近五年的代表性论文(限10项以内):
例如:主编.神经源性膀胱[M].北京:人民卫生出版社,2009.1 ISBN 978-7-117-11004-4/R·11005
1、主编.膀胱癌保留膀胱治疗学[M].湖北:湖北科学技术出版社,2025.1 ISBN 978-7-5706-2955-8
2、Li C, Kadeerhan G, Zhang T, Yeerjiang Z, Yang Y, Meng J,Wang D. Evaluating pathological complete response as an surrogate endpoint for long-term survival in patients with non-small cell lung cancer: a systematic review and meta-analysis. Int J Surg. 2025 Feb 1;111(2):2216-2226.
3、Xue B, Kadeerhan G, Sun LB, Chen YQ, Hu XF, Zhang ZK,Wang DW. Circulating exosomal miR-16-5p and let-7e-5p are associated with bladder fibrosis of diabetic cystopathy. Sci Rep. 2024 Jan 8;14(1):837.
4、Jiang Z, Kadeerhan G, Zhang J, Guo W, Guo H,Wang D. Advances in prostate-specific membrane antigen-targeted theranostics: from radionuclides to near-infrared fluorescence technology. Front Immunol. 2025 Jan 10;15:1533532.
5、Liu HP, Jia W, Kadeerhan G, Xue B, Guo W, Niu L, Wang X, Wu X, Li H, Tian J,Wang D, Lai HM. Individualized prognosis stratification in muscle invasive bladder cancer: A pairwise TP53-derived transcriptome signature. Transl Oncol. 2023 Mar;29:101629.
6、Kadeerhan G, Xue B, Wu XL, Chen WN,Wang DW. Incidence trends and survival of metastatic prostate cancer with bone and visceral involvement: 2010-2019 surveillance, epidemiology, and end results. Front Oncol. 2023 Aug 3;13:1201753.
7、Kadeerhan G, Xue B, Wu X, Hu X, Tian J,Wang D. Novel gene signature for predicting biochemical recurrence-free survival of prostate cancer and PRAME modulates prostate cancer progression. Am J Cancer Res. 2023 Jul 15;13(7):2861-2877.
8、Zhang L, Wu B,Wang D. The mechanism of long-chain acyl-CoA synthetase 3 in inhibiting cell proliferation, migration, and invasion in clear cell renal cell carcinoma. Am J Cancer Res. 2023 Mar 15;13(3):835-851.
9、Zhang Z, Xue B, Chen Y, Shao Y,Wang D. A systematic review and meta-analysis combined with bioinformatic analysis on the predictive value of E-cadherin in patients with renal cell carcinoma. Expert Rev Mol Diagn. 2024 Sep;24(9):859-871.
10、Zhai T, Ma J, Liu Y, Li H, Peng Y, Guo W, Jia J, Wu X, Jiang H, Tian J,Wang D. The role of cytoreductive radical prostatectomy and lymph node dissection in bone-metastatic prostate cancer: A population-based study. Cancer Med. 2023 Aug;12(16):16697-16706.