导师简介

姓名:郎小娥 性别:女政治面貌:民革党员学历:博士研究生毕业学位:医学博士职称:主任医师博、硕导师:博导和硕导本岗位工作年数:40.5年
研究方向:
精神分裂症与抑郁症的基础与临床研究
荣誉称号:
(1)山西省“三晋英才-拔尖骨干人才”
(2)获2023年度山西省科技进步二等奖
(3)获2019年度山西省科技进步二等奖
(4)2022年度郎小娥以第一发明人授权国际发明专利1项
学术任职:
中华医学会精神病学分会网络精神病学组委员
中国医师协会医学科普分会精神心理专委会委员
中国民族卫生协会心理健康分会常务理事
中国药物滥用防治协会理事
山西省老年医学学会精神医学分会主任委员
山西省精神科专科联盟医疗质控中心主任
近五年承担科研课题情况:
(1)中央引导地方科技发展资金项目(自由探索类基础研究),项目名称:首发分裂症糖代谢紊乱介导“脑SC-FC耦合”异常的机制研究,项目编号:YDZJSX2022A064,主持
(2)山西省“136兴医工程”领军临床专科专项(136专项),项目名称:首发精神分裂症海马体积、血浆蛋白质组分与P50改变之间交互作用的机制研究,项目编号:Y2022136006,主持
代表性论著及近五年的代表性论文(限10项以内):
近五年郎小娥以第一作者和/或通讯作者发表的10篇SCI代表性论文
[1]Xiaoe Lang,Mei Xue,Xiaocui Zang,Fengchun Wu*,Meihong Xiu*,Xiangyang Zhang*. Efficacy of low-dose risperidone in combination with sertraline in first-episode drug-naïve patients with schizophrenia: a randomized controlled open-label study [J]. J Transl Med, 2023, 21(1): 432.(唯一第一作者中科院2区IF:6.1)
[2]Meihong Xiu, Lei Zhao, Qianqian Sun,Xiaoe Lang*. Efficacy of Low-dose Olanzapine in Combination with Sertraline on Negative Symptoms and Psychosocial Functioning in Schizophrenia: A Randomized Controlled Trial [J]. Curr Neuropharmacol, 2024,22(8):1406-1413.(唯一通讯作者中科院2区IF:4.8)
[3]Xiaoe Lang*, Dongmei Wang, Dachun Chen, Meihong Xiu, Huixia Zhou, Li Wang, Bo Cao*, Xiangyang Zhang*. Association Between Hippocampal Subfields and Clinical Symptoms of First-Episode and Drug Naive Schizophrenia Patients During 12 Weeks of Risperidone Treatment [J]. Neurotherapeutics, 2022, 19(1): 399-407.(唯一第一作者/共同通讯作者中科院2区IF:5.7)
[4] Meihong Xiu, Meng Hao, Cai Liu, Maodi Sun,Xiaoe Lang*.Glucose Metabolism and Sex Hormones in Male Patients with Medication-naïve First-episode Schizophrenia: A Large-scale Cross-sectional Study[J].Curr Neuropharmacol, 2024;22(13):2263-2270.(唯一通讯作者中科院2区IF:4.8)
[5] Meihong Xiu, Wenxin Li, Yu Lan, Kaiwen Li,Xiaoe Lang*. Differentiation Across Bipolar Disorder and Major Depressive Disorder by Whole-Night Polysomnographic Findings. J Clin Psychiatry, 2024 ,14;85(3):23m15210.(唯一通讯作者中科院2区IF:4.5)
[6]Xiaoe Lang,Xiaocui Zang, Feng Yu, Meihong Xiu*. Effects of low-dose combined olanzapine and sertraline on negative and depressive symptoms in treatment-resistant outpatients with acute exacerbated schizophrenia [J]. Front Pharmacol, 2023, 14(1166507.(唯一第一作者中科院2区IF:4.4)
[7]Mei Hong Xiu,XiaoE Lang*, Da Chun Chen, Bo Cao, Thomas R. Kosten,Raymond Y. Cho, Hui Shi, Chang Wei Wei, An Shi Wu, Xiang Yang Zhang*.Cognitive Deficits and Clinical Symptoms with Hippocampal Subfields in First-Episode and Never-Treated Patients with Schizophrenia [J]. Cereb Cortex, 2021, 31(1): 89-96.(共同通讯作者中科院2区IF:4.861)
[8]Xiaoe Lang, Yang Zhou, Lei Zhao, Yinjun Gu, Xi Wu, Yuefeng Zhao, Zezhi Li*, Xiangyang Zhang*.Differences in patterns of metabolic abnormality and metabolic syndrome between early-onset and adult-onset first-episode drug-naive schizophrenia patients [J]. Psychoneuroendocrinology, 2021, 132(105344.(唯一第一作者中科院2区IF:4.693)
[9]Xiaoe Lang*, Dongmei Wang, Huixia Zhou, Li Wang, Thomas R. Kosten, Xiang-Yang Zhang*.P50 inhibition defects, psychopathology and gray matter volume in patients with first-episode drug-naive schizophrenia [J]. Asian J Psychiatr, 2023, 80(103421.(唯一第一作者/共同通讯作者中科院4区IF:9.5)
[10]Xiaoe Lang, Qinqin Liu, Hanliu Fang, Yongjie Zhou, Mattew T. Forster, Zezhi Li*, Xiangyang Zhang*.The prevalence and clinical correlates of metabolic syndrome and cardiometabolic alterations in 430 drug-naive patients in their first episode of schizophrenia [J]. Psychopharmacology, 2021, 238(12): 3643-52.(唯一第一作者中科院3区IF:4.415)