姓名：尉骁性别： 男 政治面貌：中共党员学历：研究生学位： 博士 职称：中级

博、硕导师：硕导本岗位工作年数：5

研究方向：

尘肺病合并感染细菌流行病学研究，细菌碳青霉烯耐药机制，呼吸道菌群在肺部疾病中的作用

荣誉称号：

2024年度山西医科大学第一医院“优秀青年”

学术任职：

山西省医师协会免疫微生态专业委员会常务委员

山西省医学科呼吸病学分会感染学组委员

近五年承担科研课题情况：

(1)国家自然科学基金委员会青年科学基金项目，miyX基因通过LuxS/AI-2群体感应系统提高解鸟氨酸拉乌尔菌碳青霉烯耐药流行克隆菌株质粒接合效率的机制研究，82202569

(2)山西省基础研究计划，Al-2合成酶LuxS及其甲基化修饰在肺炎克雷伯持留菌中的作用及其机制研究，20210302124635

(3)山西省卫生健康委科研课题，尘肺病患者肺部韦荣球菌代谢物L-酪氨酸加重气道炎症降低肺通气功能的机制研究，2024067

代表性论著及近五年的代表性论文（限10项以内）：

（1）Jingfen Zhang , Qiaoyu Li , Jingjing Liu , Fangfang Fan , Yiwei Shi,Xiao YuPrevalence of Hypervirulent Klebsiella pneumoniae Strains inCOVlD-19 Patients with Bacterial Co-infections, 2025, Front. Microbiol. 16:1535893.doi: 10.3389/fmicb.2025.1535893

（2）Xiao Yu,Tao Xiong, Lu Yu, Gaisheng Liu, Fan Yang, Xueqin Li, Yangyang Wei, Xiaojing Wang, Shuting Wei, Yi Jiang, Xiaomei Kong, Shouan Ren, Yiwei Shi. Gut microbiome and metabolome profiling in coal workers' pneumoconiosis: potential links to pulmonary function. Microbiology spectrum. 2024 Sep 16:e0004924. doi: 10.1128/spectrum.00049-24. Epub ahead of print. PMID: 39283109.

（3）Zhan Qing, Teng Gaoqin, Chen Weiwei,Yu Xiao.High prevalence of ST5-SCCmec II-t311 clone of methicillin-resistantStaphylococcus aureusisolated from bloodstream infections in East China. BMC Microbiology. 2024 Mar 16;24(1):89. doi: 10.1186/s12866-024-03232-5. PMID: 38491414; PMCID: PMC10943896.

（4）Lu Hong, Cheng Li, Cui Shu, Yi Xin, Li Xueqin, Liu Xiang, Kong Xiaomei,Yu Xiao. Characterizing the Loss and Acquisition of Tn2-like Transposon in Klebsiella pneumoniae: Implications for Carbapemase Gene Dissemination.Journal of Global Antimicrobial Resistance. 2024 May 6:38, 98–102. doi: 10.1016/j.jgar.2024.04.011. Epub ahead of print. PMID: 38719187.

（5）Xiao Yu, Li Cheng, Xin Yi, Bing Li, Xueqin Li, Xiang Liu, Zhihong Liu, Xiaomei Kong. Gut phageome: challenges in research and impact on human microbiota. Frontiers in Microbiology. 2024 Mar 22;15:1379382. doi: 10.3389/fmicb.2024.1379382. PMID: 38585689; PMCID: PMC10995246.

（6）Yi Xin, Lu Hong, Liu Xiang, He Junyi, Li Bing, Wang Zhelong, Zhao Yujing, Zhang Xinri,Yu Xiao. Unravelling the enigma of the human microbiome: Evolution and selection of sequencing technologies. Microbial Biotechnology. 2024 Jan;17(1):e14364. doi: 10.1111/1751-7915.14364. Epub 2023 Nov 6. PMID: 37929823; PMCID: PMC10832515.

（7）Zhang Chenwei, Xi Yujia, Zhang Yukai, He Peiyun, Su Xuesen, Li Yishan, Zhang Mengyuan, Liu Haizhao,Yu Xiao, Shi Yiwei. Causal effects between gut microbiota and pulmonary arterial hypertension: A bidirectional Mendelian randomization study. Heart Lung. 2024 Mar-Apr;64:189-197. doi: 10.1016/j.hrtlng.2024.01.002. Epub 2024 Jan 29. PMID: 38290183.

（8）Yu Xiao; Jin Ye; Zhou Wangxiao; Xiao Tingting; Wu Zhongwen; Su Junwei; Gao Hainv; Shen Ping; Zheng Beiwen; Luo Qixia; Li lanjuan; Xiao Yonghong ; Rifaximin Modulates the Gut Microbiota to Prevent Hepatic Encephalopathy in Liver Cirrhosis Without Impacting the Resistome，Frontiers in Cellular and Infection Microbiology，2022，11(76)

（9）Yu Xiao; Zheng Beiwen; Xiao，Feng; Jin Ye; Guo Lihua; Xu Hao; Luo Qixia; Xiao Yonghong ; Effect of Short-Term Antimicrobial Therapy on the Tolerance and Antibiotic Resistance of Multidrug-Resistant Staphylococcus capitis，Infection and Drug Resistance，2020，13: 2017-2026

（10）Yu Xiao;Zheng Beiwen; Zhang Jing; Xu Hao; Xiao Tingting; Zhou Yanzi; Zhang Shunti an; Zhu Yunying; Wang Yuan; Xiao Yonghong ; Comprehensive Genome Analysis of Carbapenem-Resist ant Strains of Raoultella Species，an Emerging Multidrug-Resistant Bacterium in Hospitals，Antimicrobial Agents and Chemotherapy，2019，63(12): e01367-19